Well, here is my recommended list of Apps.
HTC Home Customizer (It will load HTC Home automagically)
PointUI Home (Very awesome desktop interface)
Pretty much any Resco application, Explorer is the best
SPB Backup (makes complete backups to a memory card at any schedule you want)
SPB Shell (Another interface, similar to Home but much better, just not free)
SPB Plus (So when you click X, you really mean X and not minimize, and several other nice tweaks)
Google Maps, Microsoft Live Search, both are great if you have a GPS.
Palringo (Combine IM client, AIM, MSN, ICQ, Google) FREE